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Case Discussion AIMAH 22.07.1398

bilateral adrenal hyperplasia and subclinical hypercortisolism

  • what’s the diagnosis?
  • Are there any aberrant hormone receptors in this patient?
  • Does the patient need to a surgery?
  • Will we do in her follow up?
  • Advances in imaging techniques raised the prevalence of AI to 4.4% in radiological series compared to autopsy data (1–8.7%)
  • The prevalence is higher in patients with obesity, diabetes or hypertension and is increasing with age reaching 7–10% in individuals older than 70 years old
  • Although the majority of AIs are unilateral tumors bilateral AIs are found in up to 15%
    of cases
  • Thus, the prevalence of bilateral AI can be estimated to be 0.3–0.6% in the general population